logo CaMPDB: Calpain for Modulatory Proteolysis Database

Welcome to CaMPDB, Calpine for Modulatory Proteolysis Database.

CaMPDB is a database on calpain, a calcium-dependent protease as well as one of the most typical enzymes of modulatory proteolysis. This database mainly consists of three parts: calpain, its substrates and calpastatin (endogenous inhibitor protein specific to calpain). You can connect to each of them by clicking the corresponding term provided in the above bar. Each is organized in the same manner, having four subparts: Overview, Browse, Search, Statistics.

A unique, significant feature of this database is that one or more proteolytic sites of each substrate are collected from literature. Furthermore, systematic experiments on proteolysis of peptide fragments including these sites were conducted by our own, and resulting real values are stored in the substates part.

CaMPDB is maintained by Pathway Engineering Laboratory of Bioinformatics Center at Kyoto University, jointly working with Calpain Project Team at Tokyo Metropolitan Institute of Medical Sciences.

 

Reference

David duVerle, Ichigaku Takigawa, Yasuko Ono, Hiroyuki Sorimachi, Hiroshi Mamitsuka
CaMPDB: a Resource for Calpain and Modulatory Proteolysis
Genome Informatics 22: 202-214 (2009)