CL ........ Calpain Sequences
are collected from public databases based on annotated information "CysPc", i.e. "Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like." Thus, currently, we have no sequences of regulatory small subunits of calpain.
SB ........ Curated Calpain Substrate Sequences
are collected from literature, implying that they are experimentally confirmed.
XSB ........ Computationally Expanded Calpain Substrate Sequences
are collected computationally as follows:
CT ........ Calpastatin Sequences
are collected from public databases based on known annotations "Calpain_inhib", i.e., "Calpain inhibitor region: pfam00748" and the keyword "calpastatin" in the definition line.
Cleavage Sites of Substrates (SB+XSB)