logo CaMPDB: Calpain for Modulatory Proteolysis Database

CL0015 : Chain A, Human Calpain Protease Core Inhibited By Zllych2f

[ CaMP Format ]

* Basic Information

OrganismHomo sapiens (human)
Protein NamesCalpain-1 catalytic subunit;; Calpain-1 large subunit; Calcium-activated neutral proteinase 1; CANP 1; Calpain mu-type; muCANP; Micromolar-calpain; Cell proliferation-inducing gene 30 protein
Gene NamesPIG30; CANPL1
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
1ZCM_A N/A N/A P07384 N/A N/A N/A hsa:823

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 321 aa

Average Mass: 36.327 kDa

Monoisotopic Mass: 36.304 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Peptidase_C2 1. 23321803.11.8e-238

3. Sequence Information

Fasta Sequence: CL0015.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1ZCM (X-ray; 200 A; A=33-353), 2ARY (X-ray; 240 A; A/B=27-360)

* References

[PubMed ID: 16411745] Li Q, Hanzlik RP, Weaver RF, Schonbrunn E, Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core. Biochemistry. 2006 Jan 24;45(3):701-8.