logo CaMPDB: Calpain for Modulatory Proteolysis Database

CL1023 : Calpain-10

[ CaMP Format ]

* Basic Information

OrganismMus musculus (house mouse)
Protein NamesCalcium-activated neutral proteinase 10; CANP 10; 3.4.22.-
Gene NamesCapn8
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
Q9ESK3 N/A N/A Q9ESK3 N/A N/A N/A mmu:23830

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 666 aa

Average Mass: 74.596 kDa

Monoisotopic Mass: 74.549 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Peptidase_C2 1. 13322204.33.3e-58
Calpain_III 1. 33848852.02.3e-12
Calpain_III 2. 5076393.22.9e-07

3. Sequence Information

Fasta Sequence: CL1023.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* References

[PubMed ID: 11017071] Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI, Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet. 2000 Oct;26(2):163-75.

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