logo CaMPDB: Calpain for Modulatory Proteolysis Database

CT0181 : Chain B, Calpain Domain Vi Complexed With Calpastatin Inhibitory Domain C (Dic)

[ CaMP Format ]

* Basic Information

OrganismSus scrofa (pig)
Protein NamesCalpain small subunit 1; CSS1; Calcium-dependent protease small subunit 1; Calcium-dependent protease small subunit; CDPS; Calpain regulatory subunit; Calcium-activated neutral proteinase small subunit; CANP small subunit
Gene NamesCAPN4
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
1NX1_B N/A N/A P04574 N/A N/A N/A ssc:397587

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 173 aa

Average Mass: 19.861 kDa

Monoisotopic Mass: 19.849 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
efhand 1. 487618.40.03
efhand 2. 7810616.50.11
efhand 3. 1431708.22.7

3. Sequence Information

Fasta Sequence: CT0181.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1ALV (X-ray; 190 A; A/B=94-266), 1ALW (X-ray; 203 A; A/B=94-266), 1NX0 (X-ray; 230 A; A/B=94-266), 1NX1 (X-ray; 200 A; A/B=94-266), 1NX2 (X-ray; 220 A; A=94-266), 1NX3 (X-ray; 245 A; A=94-266)

* References

[PubMed ID: 12684003] Todd B, Moore D, Deivanayagam CC, Lin GD, Chattopadhyay D, Maki M, Wang KK, Narayana SV, A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor. J Mol Biol. 2003 Apr 18;328(1):131-46.