logo CaMPDB: Calpain for Modulatory Proteolysis Database

SB0003 : Aquaporin-0

[ CaMP Format ]

* Basic Information

OrganismRattus norvegicus (Norway rat)
Protein NamesPREDICTED: similar to major intrinsic protein of eye lens fiber [Rattus norvegicus]; similar to major intrinsic protein of eye lens fiber
Gene NamesMip; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 3 mRNAs, 19 ESTs, 27 Proteins
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
XP_343138 XM_343137 25480 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 263 aa

Average Mass: 28.208 kDa

Monoisotopic Mass: 28.191 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Major intrinsic protein 1. 32191.013.8

3. Sequence Information

Fasta Sequence: SB0003.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Source Reference: [PubMed ID: 10067969] Schey KL, Fowler JG, Shearer TR, David L, Modifications to rat lens major intrinsic protein in selenite-induced cataract. Invest Ophthalmol Vis Sci. 1999 Mar;40(3):657-67.

Cleavage sites (±10aa)


Lys238 Gly

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)

* References