logo CaMPDB: Calpain for Modulatory Proteolysis Database

SB0021 : CAPN11, [mu]/m-calpain catalytic subunit, [mu]/mCL

[ CaMP Format ]

* Basic Information

OrganismGallus gallus (chicken)
Protein Namescalpain-1 catalytic subunit [Gallus gallus]; calpain-1 catalytic subunit; CANP; mu/M-type; calpain-1 large subunit; calcium-activated neutral proteinase; Calpain-1 catalytic subunit;; Calcium-activated neutral proteinase; Calpain-1 large subunit; Mu/M-type
Gene NamesCAPN1; calpain 1, (mu/I) large subunit
Gene Locus3; chromosome 3
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_990634 NM_205303 396240 P00789 N/A N/A N/A gga:396240

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 705 aa

Average Mass: 80.351 kDa

Monoisotopic Mass: 80.300 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
--- cleavage 17 ---
Calpain family cysteine protease 1. 493451.00.0
Calpain large subunit, domain III 1. 3595091.00.0
EF-hand domain pair 1. 55660220.00.4
EF-hand domain pair 2. 61362530.00.0
EF-hand domain pair 3. 6626896.00.2

3. Sequence Information

Fasta Sequence: SB0021.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Source Reference: [PubMed ID: 2829834] Crawford C, Willis AC, Gagnon J, The effects of autolysis on the structure of chicken calpain II. Biochem J. 1987 Dec 1;248(2):579-88.

Cleavage sites (±10aa)


Arg17 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)

* References

[PubMed ID: 18727211] Zhang ZR, Liu YP, Jiang X, Du HR, Zhu Q, Study on association of single nucleotide polymorphism of CAPN1 gene with muscle fibre and carcass traits in quality chicken populations. J Anim Breed Genet. 2008 Aug;125(4):258-64.

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