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SB0034 : Neurotensin

[ CaMP Format ]

* Basic Information

OrganismBos taurus (cattle)
Protein Namesneurotensin/neuromedin N precursor [Bos taurus]; neurotensin/neuromedin N precursor; neurotensin/neuromedin N; Neurotensin/neuromedin N; Large neuromedin N; NmN-125; Neuromedin N; NN; NmN; Neurotensin; NT; Tail peptide
Gene NamesNTS; neurotensin
Gene Locus5q13; chromosome 5
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_776370 NM_173945 280881 P01156 N/A N/A N/A bta:280881

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 170 aa

Average Mass: 19.843 kDa

Monoisotopic Mass: 19.830 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Neurotensin/neuromedin N precursor 1. 51692.01.3
--- cleavage 153 (inside Neurotensin/neuromedin N precursor 5..169) ---
--- cleavage 158 (inside Neurotensin/neuromedin N precursor 5..169) ---

3. Sequence Information

Fasta Sequence: SB0034.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites] cleaved by Calpain 1 and 2

Source Reference: [PubMed ID: 6092335] Sasaki T, Kikuchi T, Yumoto N, Yoshimura N, Murachi T, Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates. J Biol Chem. 1984 Oct 25;259(20):12489-94.

Cleavage sites (±10aa)


Tyr153 Glu

iTraq-117 Signal 5813.9 () for IPYILKRQLY

iTraq-117 Signal 5031.6 () for ENKPRRPYIL

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)


Arg158 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)

* References

[PubMed ID: 19393038] Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marcais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL, A whole-genome assembly of the domestic cow, Bos taurus. Genome Biol. 2009;10(4):R42. doi: 10.1186/gb-2009-10-4-r42. Epub 2009 Apr 24.

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