logo CaMPDB: Calpain for Modulatory Proteolysis Database

SB0057 : MAP2c

[ CaMP Format ]

* Basic Information

OrganismRattus norvegicus (Norway rat)
Protein Namesunnamed protein product [Rattus norvegicus]; Microtubule-associated protein 2; MAP-2
Gene NamesMtap2
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
CAA35667 N/A N/A P15146 N/A N/A N/A rno:25595

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 467 aa

Average Mass: 49.299 kDa

Monoisotopic Mass: 49.270 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
RII binding domain 1. 861031.03.8
--- cleavage 99 (inside RII binding domain 86..103) ---
Tau and MAP protein, tubulin-binding repeat 1. 3043315.00.1
Tau and MAP protein, tubulin-binding repeat 2. 3323611.00.6
Tau and MAP protein, tubulin-binding repeat 3. 3633941.00.5
Tau and MAP protein, tubulin-binding repeat 4. 3954121.00.0

3. Sequence Information

Fasta Sequence: SB0057.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Source Reference: [PubMed ID: 14988399] Tompa P, Buzder-Lantos P, Tantos A, Farkas A, Szilagyi A, Banoczi Z, Hudecz F, Friedrich P, On the sequential determinants of calpain cleavage. J Biol Chem. 2004 May 14;279(20):20775-85. Epub 2004 Feb 26.

Cleavage sites (±10aa)


Thr99 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)

* References

[PubMed ID: 2326166] Doll T, Papandrikopoulou A, Matus A, Nucleotide and amino acid sequences of embryonic rat MAP2c. Nucleic Acids Res. 1990 Jan 25;18(2):361.