logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB0178 : micromolar calcium activated neutral protease 1 [Bos taurus]

[ CaMP Format ]

This entry is computationally expanded from SB0020

* Basic Information

OrganismBos taurus (cattle)
Protein NamesCalpain-1 catalytic subunit;; Calpain-1 large subunit; Calcium-activated neutral proteinase 1; CANP 1; Calpain mu-type; muCANP; Micromolar-calpain; micromolar calcium activated neutral protease 1
Gene NamesCAPN1
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAF64504 N/A N/A Q27970 N/A N/A N/A bta:281661

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 716 aa

Average Mass: 82.249 kDa

Monoisotopic Mass: 82.197 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
--- cleavage 15 ---
Peptidase_C2 1. 55354797.39.8e-237
Calpain_III 1. 365524371.31.8e-108
efhand 1. 5485750.120
efhand 2. 59161916.60.11
efhand 3. 62164915.40.23
efhand 4. 6867136.24.5

3. Sequence Information

Fasta Sequence: XSB0178.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)


Ser15 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)

* References

[PubMed ID: 11048924] Smith TP, Casas E, Rexroad CE 3rd, Kappes SM, Keele JW, Bovine CAPN1 maps to a region of BTA29 containing a quantitative trait locus for meat tenderness. J Anim Sci. 2000 Oct;78(10):2589-94.