logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2831 : insulin-like growth factor binding protein 4 [Ovis aries]

[ CaMP Format ]

This entry is computationally expanded from SB0070

* Basic Information

OrganismOvis aries (sheep)
Protein NamesInsulin-like growth factor binding protein-4; insulin-like growth factor binding protein 4; insulin-like growth factor-binding protein 4
Gene NamesIGFBP4; igfbp4; insulin-like growth factor binding protein 4
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001127774 NM_001134302 443470 B5AZT5_SHEEP N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 258 aa

Average Mass: 27.916 kDa

Monoisotopic Mass: 27.898 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
IGFBP 1. 2785101.62.6e-27
--- cleavage 143 ---
--- cleavage 159 ---
--- cleavage 107 ---
Thyroglobulin_1 1. 174249144.04.7e-40

3. Sequence Information

Fasta Sequence: XSB2831.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

3 [sites]

Cleavage sites (±10aa)


Leu143 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)


Ile159 Gly

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)


Glu107 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)

* References

[PubMed ID: 7531449] Carr JM, Grant PA, Francis GL, Owens JA, Wallace JC, Walton PE, Isolation and characterization of ovine IGFBP-4: protein purification and cDNA sequence. J Mol Endocrinol. 1994 Oct;13(2):219-36.