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XSB2918 : Metabotropic glutamate receptor 1

[ CaMP Format ]

This entry is computationally expanded from SB0007

* Basic Information

OrganismHomo sapiens (human)
Protein NamesmGluR1
Gene NamesGPRC1A, MGLUR1; GPRC1A; MGLUR1
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
Q13255 N/A N/A GRM1_HUMAN N/A N/A N/A hsa:2911

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 1194 aa

Average Mass: 132.367 kDa

Monoisotopic Mass: 132.282 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
ANF_receptor 1. 77485312.21.1e-90
NCD3G 1. 51957194.83.1e-25
7tm_3 1. 596845431.11.8e-126
DUF1210 1. 8601027-108.17.5
--- cleavage 936 (inside DUF1210 860..1027) ---
GluR_Homer-bdg 1. 11441194112.02e-30

3. Sequence Information

Fasta Sequence: XSB2918.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] TAVIKPLTKS936-YQGSGKSLTF

Ser936 Tyr

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Thr927Ala928Val929Ile930Lys931Pro932Leu933Thr934Lys935Ser936
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Tyr937Gln938Gly939Ser940Gly941Lys942Ser943Leu944Thr945Phe946

Sequence conservation (by blast)

* References

[PubMed ID: 7476890] Desai MA, Burnett JP, Mayne NG, Schoepp DD, Cloning and expression of a human metabotropic glutamate receptor 1 alpha: enhanced coupling on co-transfection with a glutamate transporter. Mol Pharmacol. 1995 Oct;48(4):648-57.

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