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XSB2962 : plasma membrane calcium ATPase 2 isoform 1 [Mus musculus]

[ CaMP Format ]

This entry is computationally expanded from SB0056

* Basic Information

OrganismMus musculus (house mouse)
Protein NamesPlasma membrane calcium-transporting ATPase 2; PMCA2;; Plasma membrane calcium ATPase isoform 2; Plasma membrane calcium pump isoform 2; plasma membrane calcium ATPase 2 isoform 1; wriggle; deaf waddler
Gene NamesAtp2b2; Pmca2; ATPase, Ca++ transporting, plasma membrane 2
Gene Locus6 49.5 cM; chromosome 6
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_033853 NM_009723 11941 AT2B2_MOUSE N/A N/A N/A mmu:11941

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 1198 aa

Average Mass: 132.588 kDa

Monoisotopic Mass: 132.503 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Cation_ATPase_N 1. 4112475.02.8e-19
E1-E2_ATPase 1. 156444225.11.8e-64
Hydrolase 1. 44879655.61.9e-13
Cation_ATPase_C 1. 8571039210.73.8e-60

3. Sequence Information

Fasta Sequence: XSB2962.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)


Arg1079 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)

* References

[PubMed ID: 18848933] Souayah N, Sharovetskaya A, Kurnellas MP, Myerson M, Deitch JS, Elkabes S, Reductions in motor unit number estimates (MUNE) precede motor neuron loss in the plasma membrane calcium ATPase 2 (PMCA2)-heterozygous mice. Exp Neurol. 2008 Dec;214(2):341-6. Epub 2008 Sep 19.

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