logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2971 : plasma membrane Ca2+ pumping ATPase

[ CaMP Format ]

This entry is computationally expanded from SB0056

* Basic Information

OrganismHomo sapiens (human)
Protein NamesPlasma membrane calcium-transporting ATPase 1; PMCA1;; Plasma membrane calcium pump isoform 1; Plasma membrane calcium ATPase isoform 1
Gene NamesATP2B1; PMCA1
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAA74511 N/A N/A AT2B1_HUMAN N/A N/A N/A hsa:490

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 1220 aa

Average Mass: 134.710 kDa

Monoisotopic Mass: 134.625 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
efhand 1. 13413.97.8
Cation_ATPase_N 1. 4412784.92.8e-22
E1-E2_ATPase 1. 158465232.31.2e-66
Hydrolase 1. 46981863.77.1e-16
Cation_ATPase_C 1. 8791061204.33.3e-58

3. Sequence Information

Fasta Sequence: XSB2971.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)


Arg1101 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)

* References

[PubMed ID: 2844759] Verma AK, Filoteo AG, Stanford DR, Wieben ED, Penniston JT, Strehler EE, Fischer R, Heim R, Vogel G, Mathews S, et al., Complete primary structure of a human plasma membrane Ca2+ pump. J Biol Chem. 1988 Oct 5;263(28):14152-9.