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XSB2991 : major intrinsic protein of lens fiber [Ovis aries]

[ CaMP Format ]

This entry is computationally expanded from SB0003

* Basic Information

OrganismOvis aries (sheep)
Protein NamesLens fiber major intrinsic protein; Aquaporin-0; major intrinsic protein of lens fiber; aquaporin 0
Gene NamesMIP; AQP0; major intrinsic protein of lens fiber
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001153230 NM_001159758 100294602 MIP_SHEEP N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 263 aa

Average Mass: 28.263 kDa

Monoisotopic Mass: 28.245 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
MIP 1. 3219429.45.6e-126

3. Sequence Information

Fasta Sequence: XSB2991.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1SOR (EM; 300 A; A=5-239), 2B6O (EM; 190 A; A=1-263)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)


Lys238 Gly

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'

Sequence conservation (by blast)

* References

[PubMed ID: 17869130] Scheuring S, Buzhynskyy N, Jaroslawski S, Goncalves RP, Hite RK, Walz T, Structural models of the supramolecular organization of AQP0 and connexons in junctional microdomains. J Struct Biol. 2007 Dec;160(3):385-94. Epub 2007 Jul 28.

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